Dating of propofol
By contrast, thiopental has less negative inotropic effects on hemodynamics compared to propofol, which could be suitable to prevent hypotension during GA induction.In the present age-stratified, randomized, assessor-blinded study, using the Clear Sight = 20, each group).
You’ll find data on ultra-short acting drugs such as propofol and remifentanil.
This data helps, but the skill of waking up a patient on demand is more an art than a science. Anesthesiologist’s Manual of Surgical Procedures, (4 Edition, 2009), edited by Jaffe and Samuels, has an Appendix that lists Standard Adult Anesthetic Protocols, but there is little specific information on how to titrate the drugs to ensure a timely wakeup.
Propofol is commonly used with remifentanil for induction of general anesthesia (GA); however, it often leads to hypotension.
Intraoperative hypotension is associated with postoperative adverse events.